Involuntary movement in infants during vitamin B12 treatment
Megaloblastic anemia is rare in infants and is generally due to vitamin B12 (cobalamin) deficiency in the mother. Neurologic symptoms of vitamin B12 deficiency include irritability, failure to thrive, hypotonia, and developmental regression/delay. Herein we present 2 infants with vitamin B12 that developed movement disorder 5 d after initiation of vitamin B12 treatment. Symptoms included tremor and myoclonus, involving in particular the face, tongue, and hands. Clinical findings in infants associated with vitamin B12 deficiency vary, and temporary involuntary movement can be observed during vitamin B12 therapy.

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Authors: Ayşe Tosun, Yusuf Ziya Aral, Emre Çeçen, Ayvaz Aydoğdu, Bilin Çetinkaya Çakmak

Keywords: İstemsiz hareketler, B12 vitamini eksikliği, süt çocuğu

• Year: 2011
• Number: 4
• Referance No: 84840

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• 

  Figure 1. Coronal T1-Weighted Cranial MRI Shows Bilateral Atrophy in the Frontoparietal Region and Dilatation in the Ventricles
• 

  Figure 2. Axial T1-Weighted Cranial MRI Shows Severe Bilateral Cortical Frontoparietal Atrophy and Ventricular Dilatation