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Myeloid Sarcoma: An Unusual Presentation of Acute Promyelocytic Leukemia Causing Spinal Cord Compression
Figure 1: T2 weighted MRI of the patient’s spine. (A+B): Images taken at presentation showing an intraspinal mass (white arrows) located extradurally between T2 and T4 vertebral bodies with multiple hyperintense bony lesions (black arrows) on T12, L1, L2, L4 and L5 vertebral bodies. (C+D): Images taken 1 month after treatment showing no evidence of intraspinal mass but the bony lesions on thoracic and lumbar vertebral bodies were persistent (black arrows). (E): Image taken after the third consolidation therapy showing a few residual bony lesions on L1 and L2 vertebral bodies (black arrows).
Myeloid Sarcoma: An Unusual Presentation of Acute Promyelocytic Leukemia Causing Spinal Cord Compression
Figure 2: Flow cytometric immunophenotyping of the bone marrow aspirate showing leukemic cells which are CD45 (+), CD13 (+), CD117 (+), cytoplasmic MPO (+), CD34 (-), HLA-DR (-), CD22 (-) and cytoplasmic CD3 (-).
Myeloid Sarcoma: An Unusual Presentation of Acute Promyelocytic Leukemia Causing Spinal Cord Compression
Figure 3: Diffuse infiltration of neoplastic cells in the bone marrow biopsy (H&E, x40). Immunohistochemical analysis of the infiltrating neoplastic cells showed positive reaction with CD117 (CD117 x40) and negative reaction with CD34 (CD34 x40) and HLA-DR (HLA-DR x40).
A Novel Homozygous Nucleotide Deletion in the JAK2 Gene in a Pediatric Patient with B-cell Precursor Acute Lymphoblastic Leukemia
Figure 1: Sequencing analysis of exon 12 of the JAK2 gene in the presented case at admission shows deletion of 1584 del G.
A Novel Homozygous Nucleotide Deletion in the JAK2 Gene in a Pediatric Patient with B-cell Precursor Acute Lymphoblastic Leukemia
Figure 2: Sequencing analysis of exon 12 of the JAK2 gene in the presented case while in remission.
Cerebellar Granulocytic Sarcoma: A Case Report
Figure 1: Axial (A) and sagittal (B-C) T1- and T2-weighted MRI with Gd-DTPA show the linear heterogeneously enhanced mass in the right cerebellar hemisphere.
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Figure 2: Photomicrograph shows diffuse undifferentiated mononuclear cells (hematoxylin and eosin, 100x).
C-Reactive Protein in the Follow-up and Estimation of Infections in Acute Leukemic Patients
Figure 1. Values of serum CRP in patients with fever resolution under antipseudomonal beta-lactam antibiotic and aminoglycoside therapy (n= 35).
C-Reactive Protein in the Follow-up and Estimation of Infections in Acute Leukemic Patients
Figure 2. Values of serum CRP in patients with fever resolution under antipseudomonal beta-lactam antibiotic + aminoglycoside + vancomycin therapy (n= 11).
C-Reactive Protein in the Follow-up and Estimation of Infections in Acute Leukemic Patients
Figure 3. Values of serum CRP in patients with fever under amphotericin B therapy (n= 23).
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